Acute conjunctivitis with episcleritis and anterior uveitis linked to adiaspiromycosis and freshwater sponges, Amazon region, Brazil, 2005.

摘要: We conducted an epidemiologic investigation of outbreak ocular disease among children to determine whether the was linked Emmonsia sp., a rarely-reported fungus and agent adiaspiromycosis. Using unmatched case–control study design, we compared case-patients with asymptomatic controls randomly selected from population. Scleral biopsies were analyzed microscopically. Of 5,084 examined, 99 identified; mean age (+1 SD) 11.0 ± 4.4 years. Symptoms included photophobia (57%), pain (42%), blurred vision (40%). In multivariate analysis, risk factors diving in Araguaia River (odds ratio 5.2; 95% confidence interval 2.4–12.0). Microscopy identified foreign bodies consistent adiaconidia. This probably resulted foreign-body–type reactions adiaspiromycosis conidia after initial irritation caused by conjunctival contact spicules sponges river. Symptomatic responded corticosteroid treatment. Adiaspiromycosis is preventable cause Amazon region.