Detecting and treating Clostridium difficile infections in patients with inflammatory bowel disease.
作者： Ashwin N. Ananthakrishnan
DOI: 10.1016/J.GTC.2012.01.003
关键词:
摘要: The prevalence of CDI in patients with IBD has increased over the last decade. excess morbidity and mortality associated appears to be greater than those without preexisting bowel disease. risk factors for non-IBD populations appear similar; unique IBD-related are use maintenance immunosuppression extent severity prior colitis. Nevertheless, a significant proportion CDI-IBD may have disease traditional (ie, antibiotic use, recent hospitalization). absence such must not preclude considering differential diagnosis presenting flare. Vancomycin metronidazole similar efficacy vancomycin being preferred agent severe Early surgical consultation is key improving outcomes Several gaps research exist; prospective multicenter cohorts essential improve our understanding impact on define appropriate therapeutic regimens patient outcomes.
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