The regulatory crosstalk between kinases and proteases in cancer.
作者： Carlos López-Otín , Tony Hunter
DOI: 10.1038/NRC2823
关键词:
摘要: Many proteases are regulated by phosphorylation, and many kinases proteolytic cleavage. This Review examines kinase–protease interactions their functional effects in cancer depth, revealing the enormous diversity complexity of this crosstalk.
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Molly R Darragh, Ami S Bhatt, Charles S Craik, MT-SP1 proteolysis and regulation of cell-microenvironment interactions Frontiers in Bioscience. ,vol. 13, pp. 528- 539 ,(2008) , 10.2741/2698
Kwan-Hyuck Baek, Hyun-Jin Shin, Sook-Jung Jeong, Joong-Won Park, Frank McKeon, Chang-Woo Lee, Chang-Min Kim, Caspases-dependent cleavage of mitotic checkpoint proteins in response to microtubule inhibitor. Oncology Research. ,vol. 15, pp. 161- 168 ,(2005) , 10.3727/096504005776367906
A Kishimoto, K Mikawa, K Hashimoto, I Yasuda, S Tanaka, M Tominaga, T Kuroda, Y Nishizuka, Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain). Journal of Biological Chemistry. ,vol. 264, pp. 4088- 4092 ,(1989) , 10.1016/S0021-9258(19)84966-9
Kai Prager, Lihua Wang-Eckhardt, Regina Fluhrer, Richard Killick, Esther Barth, Heike Hampel, Christian Haass, Jochen Walter, A Structural Switch of Presenilin 1 by Glycogen Synthase Kinase 3β-mediated Phosphorylation Regulates the Interaction with β-Catenin and Its Nuclear Signaling Journal of Biological Chemistry. ,vol. 282, pp. 14083- 14093 ,(2007) , 10.1074/JBC.M608437200
Aaron Ciechanover, Proteolysis: from the lysosome to ubiquitin and the proteasome. Nature Reviews Molecular Cell Biology. ,vol. 6, pp. 79- 87 ,(2005) , 10.1038/NRM1552
Amaury Fernández-Montalván, Tewis Bouwmeester, Gerard Joberty, Robert Mader, Marion Mahnke, Benoit Pierrat, Jean-Marc Schlaeppi, Susanne Worpenberg, Bernd Gerhartz, Biochemical characterization of USP7 reveals post‐translational modification sites and structural requirements for substrate processing and subcellular localization FEBS Journal. ,vol. 274, pp. 4256- 4270 ,(2007) , 10.1111/J.1742-4658.2007.05952.X
Peter Blume-Jensen, Tony Hunter, Oncogenic kinase signalling. Nature. ,vol. 411, pp. 355- 365 ,(2001) , 10.1038/35077225
Antje Trümpler, Bernhard Schlott, Peter Herrlich, Peter A. Greer, Frank-D. Böhmer, Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B FEBS Journal. ,vol. 276, pp. 5622- 5633 ,(2009) , 10.1111/J.1742-4658.2009.07255.X
Victor Quesada, Gonzalo R Ordonez, Luis M Sanchez, Xose S Puente, Carlos López-Otín, The Degradome database: mammalian proteases and diseases of proteolysis. Nucleic Acids Research. ,vol. 37, pp. 239- 243 ,(2009) , 10.1093/NAR/GKN570
J. Senft, B. Helfer, S. M. Frisch, Caspase-8 Interacts with the p85 Subunit of Phosphatidylinositol 3-Kinase to Regulate Cell Adhesion and Motility Cancer Research. ,vol. 67, pp. 11505- 11509 ,(2007) , 10.1158/0008-5472.CAN-07-5755