Genetics and Epigenetics of Eating Disorders
作者： Cynthia Bulik , Zeynep Yilmaz , Andrew HArdaway
DOI: 10.2147/AGG.S55776
关键词:
摘要: Eating disorders (EDs) are serious psychiatric conditions influenced by biological, psychological, and sociocultural factors. A better understanding of the genetics these complex traits development more sophisticated molecular biology tools have advanced our etiology EDs. The aim this review is to critically evaluate literature on genetic research conducted three major EDs: anorexia nervosa (AN), bulimia (BN), binge eating disorder (BED). We will first diagnostic criteria, clinical features, prevalence, prognosis AN, BN, BED, followed a family, twin, adoption studies. then history studies EDs covering linkage analysis, candidate gene association studies, genome-wide study rare variants in Our also incorporates translational perspective animal models ED-related phenotypes. Finally, we nascent field epigenetics look forward future directions for ED research.
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