Physiological and behavioral effects of the mycotoxin deoxynivalenol in Tenebrio molitor larvae

摘要: Abstract Deoxynivalenol (DON) is one of the most prevalent type B trichothecene mycotoxins present in cereals such as: wheat, rye, barley, oats and corn. It initiates a wide range toxic effects on human animal health. As an edible insect species for growing population, Tenebrio molitor typically fed cereal bran or flour. In study T. molitor L. larvae were grown two weeks wheat artificially contaminated with DON at four concentrations: 4.9 μg/g, 8 μg/g, 16 μg/g 25 μg/g. The intake survival, growth, activity antioxidant enzymes - superoxide dismutase (SOD) catalase (CAT) phase II biotransformation enzyme glutathione-S-transferase (GST), protein content locomotor monitored two-month-old larvae. revealed that concentrations ranging from 4.9 to 25 μg/g reduced larval body weight content. Furthermore, it increased SOD GST activity, had no effect CAT activity. Also, this showed presence these has direct detrimental but observed particularly pronounced given highest concentration These finding reveals up able induce dose-dependent physiological behavioral changes