Genomic Landscape of Ovarian Cancer

摘要: Epithelial ovarian cancer (EOC) remains one of the most challenging areas research as it is a highly heterogeneous disease from both molecular and etiological points view. Furthermore, EOC fifth leading cause cancer-related deaths among women, death gynecological cancer. Early detection paramount to increase survival, but only 25% all are found at an early stage; furthermore, tumors that appear similar based on traditional clinical histopathologic features may respond very differently therapy. At biological level, relevant need for new classification would enable identification targetable pathways predict outcome disease; open issues patients with drug-resistant cancers so alternative therapeutic modalities can be offered.