Four new epoxy taxanes from needles of Taxus cuspidata (Taxaceae).
作者： Qing-Wen Shi , Cong-Mei Cao , Ji-Shun Gu , Hiromasa Kiyota
DOI: 10.1080/14786410500049426
关键词:
摘要: Four new epoxy taxoids were isolated from the needles of Taxus cuspidata. Their structures established as 2α,9α-diacetoxy-5α-cinnamoyloxy-11,12-epoxy-10β-hydroxytax-4(20)-en-13-one (1), 2α,10β-diacetoxy-5α-cinnamoyloxy-11,12-epoxy-9α-hydroxytax-4(20)-en-13-one (2), 2α,9α-diacetoxy-11,12-epoxy-10β,20-dihydroxytax-4-en-13-one (3) and 2α,10β-diacetoxy-11,12-epoxy-9α,20-dihydroxytax-4-en-13-one (4) on basis spectral analysis including 1H-NMR, 13C-NMR, 1H–1H-COSY, HSQC, HMBC HRFABMS. Compounds 3 4 are first example 11,12-epoxy with C-4 double bond found in T.
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