The frequency of isoniazid acetylase enzyme deficiency among Egyptians.

作者: Nemat Hashem , Sami Khalifa , Assma Nour

DOI: 10.1002/AJPA.1330310114

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摘要: The frequency of isoniazid slow inactivators is very high among Eqyptians, 82% have more than 0.91 γ/ml free INH in serum specimens obtained six hours after a single dose 10 mgm/kgm. incidence the allele for acetylase enzyme deficiency estimated at 0.9059 and that heterozygous carrier this 0.1705.

参考文章(2)
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H. William Harris, CURRENT CONCEPTS OF THE METABOLISM OF ANTITUBERCULOUS AGENTS Annals of the New York Academy of Sciences. ,vol. 106, pp. 43- 47 ,(2006) , 10.1111/J.1749-6632.1963.TB16619.X