Cigarette smoking and non-fatal myocardial infarction in women: is the relation independent of coronary artery disease?

摘要: The relation of cigarette smoking to both coronary disease and non-fatal myocardial infarction was examined in a cross sectional study 1053 women who underwent arteriography. As compared with the 489 had never smoked cigarettes, ever-smokers (mean duration smoking, 25 years) were 1.6 times as likely have significant stenotic 1.9 suffered infarction. These associations strongest under 50 years age, odds ratios 3.5 for artery 4.5 Although extent prior strongly associated, cigarettes remained at increased risk even after their been taken into account. For example, heavy smokers (greater than 30 pack-years) 2.3 non-smokers; controlling (in addition age other factors) reduced estimated relative only 1.9. Stratified analyses showed that this clinical among evident all levels occlusion, minimal disease. results, collected time arteriography, suggest non-atherogenic mechanisms may be important aetiology smoke cigarettes.