Influence of Admission Blood Glucose in Predicting Outcome in Patients With Spontaneous Intracerebral Hematoma.

作者: Lakshman I. Kongwad , Ajay Hegde , Girish Menon , Rajesh Nair

DOI: 10.3389/FNEUR.2018.00725

关键词:

摘要: Background and Aims Hyperglycemia or elevated blood glucose levels have been associated with poor outcomes in patients ischemic stroke yet control of hyperglycemia has not resulted good outcomes. The prognostic value spontaneous intracerebral hemorrhage (SICH) is completely understood. High admission (ABG) values mitigated by other prognosticators like large hematoma volume, intraventricular extension (IVE) GCS. aim this study was to evaluate the effects at admission, on mortality functional discharge 3 months follow up while considering baseline demographics, radiological clinical indicators severity ICH. Methods: This a retrospective observational conducted tertiary care. Patients SICH were enrolled from prospective register maintained our hospital. Blood recorded admission. traumatic hematomas, vascular malformations, aneurysms coagulation abnormalities excluded study. Results A total 510 included We dichotomised cohort into two groups, group ABG>160mg/dl B ABG<160mg/dl. Mean these groups 220.73mg/dl 124.37mg/dl respectively, having twice mortality. mRS better Group (p=<0.001) as compared A. Age, GCS, volume hematoma, ABG, IVE Hydrocephlaus significant predictors outcome univariate analysis p <0.05. relationship between ABG (P=0.249, 95%CI 0.948 1.006) (P=0.538, 0.997-1.005) failed reach statistical significance multivariate logistic regression. Volume GCS stronger morbidity. Conclusion Admission an independent predictor when adjusted age, volume. Catastrophic high which appears be stress response bleeding. effect probably multifactorial warrant further research.

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