Predicting recurrence after curative resection for gastric cancer

作者: L.C. Barchi , O.K. Yagi , C.E. Jacob , D.R. Mucerino , U. Ribeiro

DOI: 10.1016/J.EJSO.2015.08.164

关键词:

摘要: Abstract Background Most nomograms for Gastric Cancer (GC) were developed to predict overall survival (OS) after curative resection. The Italian Research Group (GIRCG) prognostic scoring system (PSS) was designed the recurrence risk treatment based on pathologic tumor stage and performed (D1–D2/D3 lymphadenectomy). This study carried out externally validate GIRCG's PSS. Patients methods Adopting same criteria used by GIRCG build PSS, 185 patients with GC operated intention selected. median follow-up period 77.8 months (1.93–150.8) all 102.5 (60.9–150.8) free of disease. NRI (net reclassification improvement) calculated estimate improvement in using PSS place TNM system. Results occurred 70 (37.8%) patients. mean time 22.2 (range 1.9–98.1) months. For recurrence, gain proportion 0.257 (p  Conclusion which predicts likelihood radical surgical GC, is more accurate than mainly high-risk Yet, does not have effectiveness low-risk patients, overestimating chance occurs even disease-free

参考文章(46)
Xavier Paoletti, Koji Oba, Tomasz Burzykowski, Stefan Michiels, Yasuo Ohashi, Jean-Pierre Pignon, Philippe Rougier, Junichi Sakamoto, Daniel Sargent, Mitsuru Sasako, Eric Van Cutsem, Marc Buyse, Benefit of Adjuvant Chemotherapy for Resectable Gastric Cancer A Meta-analysis JAMA. ,vol. 303, pp. 1729- 1737 ,(2010) , 10.1001/JAMA.2010.534
Daniele Marrelli, Stefano Caruso, Franco Roviello, Prognostic Factors and Score Systems in Gastric Cancer Surgery in the Multimodal Management of Gastric Cancer. pp. 35- 42 ,(2012) , 10.1007/978-88-470-2318-5_5
Daniele Marrelli, Karol Polom, Giovanni De Manzoni, Paolo Morgagni, Gian Luca Baiocchi, Franco Roviello, Multimodal treatment of gastric cancer in the west: Where are we going? World Journal of Gastroenterology. ,vol. 21, pp. 7954- 7969 ,(2015) , 10.3748/WJG.V21.I26.7954
Daniele Marrelli, Paolo Morgagni, Giovanni de Manzoni, Arianna Coniglio, Alberto Marchet, Luca Saragoni, Guido Tiberio, Franco Roviello, Italian Research Group for Gastric Cancer (IRGGC, Prognostic Value of the 7th AJCC/UICC TNM Classification of Noncardia Gastric Cancer: Analysis of a Large Series From Specialized Western Centers Annals of Surgery. ,vol. 255, pp. 486- 491 ,(2012) , 10.1097/SLA.0B013E3182389B1A
Hong Yang, Chenghai Zhang, Zhendan Yao, Nan Zhang, Jiafu Ji, Hong Qu, Xiangqian Su, Donglai Chen, Beihai Jiang, Jiadi Xing, Maoxing Liu, Ming Cui, Yiqiang Liu, Zaozao Wang, Lei Chen, Validation of the Memorial Sloan-Kettering Cancer Center Nomogram to Predict Disease-Specific Survival after R0 Resection in a Chinese Gastric Cancer Population PLoS ONE. ,vol. 8, pp. e76041- ,(2013) , 10.1371/JOURNAL.PONE.0076041
Raquel Seruca, Nuno R. Santos, Leonor David, Miguel Constáncia, Helena Barroca, Fátima Carneiro, Mario Seixas, Päivi Peltomäki, Ragnhild Lothe, Manuel Sobrinho-Simöes, Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile. International Journal of Cancer. ,vol. 64, pp. 32- 36 ,(1995) , 10.1002/IJC.2910640108
Vivian E. Strong, Kyo Young Song, Cho Hyun Park, Lindsay M. Jacks, Mithat Gonen, Manish Shah, Daniel G. Coit, Murray F. Brennan, Comparison of Gastric Cancer Survival Following R0 Resection in the United States and Korea Using an Internationally Validated Nomogram Annals of Surgery. ,vol. 251, pp. 640- 646 ,(2010) , 10.1097/SLA.0B013E3181D3D29B
Jason S. Gold, Laura H. Tang, Mithat Gönen, Daniel G. Coit, Murray F. Brennan, Peter J. Allen, Utility of a Prognostic Nomogram Designed for Gastric Cancer in Predicting Outcome of Patients with R0 Resected Duodenal Adenocarcinoma Annals of Surgical Oncology. ,vol. 14, pp. 3159- 3167 ,(2007) , 10.1245/S10434-007-9542-1