Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment
作者： Yuanyuan Zhao , Zhao , Guo , Huang , Lin
DOI: 10.2147/OTT.S46498
关键词:
摘要: Purpose To determine whether 5-fluorouracil (5-FU) sensitivity is associated with the mRNA expressions of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and thymidine phosphorylase (TP) in patients hepatocellular carcinoma (HCC) treated 5-FU-based transarterial chemoembolization (TACE).
sci-hub.se 参考文章(42)
Meng-Sen Li, Ping-Feng Li, Qian Chen, Guo-Guang Du, Gang Li, Alpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cells World Journal of Gastroenterology. ,vol. 10, pp. 819- 824 ,(2004) , 10.3748/WJG.V10.I6.819
Toda G, Komuro O, Koike K, Onoda H, Enomoto Y, Kawabe T, Tsuno S, Itsubo M, Two cases of transcatheter therapy to hepatocellular carcinoma supplied by the right internal mammary artery The Japanese journal of gastro-enterology. ,vol. 97, pp. 585- 589 ,(2000)
Zenro Nihei, Hiroyuki Uetake, Hiroyuki Yamada, Yoshinori Shirota, Kenichi Sugihara, Naoto Nishi, Wataru Ichikawa, Renzo Hirayama, Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. Clinical Cancer Research. ,vol. 9, pp. 786- 791 ,(2003)
Robert B. Diasio, Ruiwen Zhang, Zhihong Lu, Dihydropyrimidine Dehydrogenase Activity in Human Peripheral Blood Mononuclear Cells and Liver: Population Characteristics, Newly Identified Deficient Patients, and Clinical Implication in 5-Fluorouracil Chemotherapy Cancer Research. ,vol. 53, pp. 5433- 5438 ,(1993)
Mimi C. Yu, Chi-Chun Mo, Fu-Sun Yeh, Si Luo, Brian E. Henderson, Myron J. Tong, Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China. Cancer Research. ,vol. 49, pp. 2506- 2509 ,(1989)
Robert B. Diasio, Martin R. Johnson, Dihydropyrimidine Dehydrogenase: Its Role in 5-Fluorouracil Clinical Toxicity and Tumor Resistance Clinical Cancer Research. ,vol. 5, pp. 2672- 2673 ,(1999)
H M Pinedo, G F Peters, Fluorouracil: biochemistry and pharmacology. Journal of Clinical Oncology. ,vol. 6, pp. 1653- 1664 ,(1988) , 10.1200/JCO.1988.6.10.1653
Tatsuo Nakagawa, Yosuke Otake, Kazuhiro Yanagihara, Ryo Miyahara, Shinya Ishikawa, Masakazu Fukushima, Hiromi Wada, Fumihiro Tanaka, Expression of thymidylate synthase is correlated with proliferative activity in non-small cell lung cancer (NSCLC) Lung Cancer. ,vol. 43, pp. 145- 149 ,(2004) , 10.1016/J.LUNGCAN.2003.09.004
Yehuda Z. Patt, Richard Pazdur, Ruth Smith, Bernard Levin, Mark Roh, Boris Yoffe, Christine A. Noonan, Chusilp Charnsangavej, Harold Fischer, Karen Cleary, Low serum alpha-fetoprotein level in patients with hepatocellular carcinoma as a predictor of response to 5-FU and interferon-alpha-2b. Cancer. ,vol. 72, pp. 2574- 2582 ,(1993) , 10.1002/1097-0142(19931101)72:9<2574::AID-CNCR2820720911>3.0.CO;2-L
MC Kew, MC Yu, MA Kedda, A Coppin, A Sarkin, J Hodkinson, The relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in Southern African blacks Gastroenterology. ,vol. 112, pp. 184- 187 ,(1997) , 10.1016/S0016-5085(97)70233-6