Distribution of P2X receptor subtypes in the rat female reproductive tract at late pro-oestrus/early oestrus.

摘要: Using immunohistochemistry techniques, we have examined the female reproductive organs of rat in late pro-oestrus/early oestrus for presence purine nucleotide P2X1-7 receptors. In contrast to male genital and urinary tract, P2X1 receptors were present weakly, if at all, on smooth muscle membranes, except blood vessels, whereas P2X2 immunoreactivity was ovary uterus as well vessels. Neither nor fallopian tubes. P2X5 seen differentiating cell layers stratified squamous vaginal epithelium also very early stages ovarian follicular development; P2X6 secondary follicles. P2X7 receptors, markers programmed death, keratinised exfoliating superficial endometrial cells. The possible biological significance these signalling molecules tract is discussed.