Entorhinal cortex stimulation modulates amygdala and piriform cortex responses to olfactory bulb inputs in the rat.

摘要: The rodent olfactory bulb sends direct projections to the piriform cortex and two structures intimately implicated in memory processes, entorhinal amygdala. has monosynaptic with amygdala is therefore a position modulate input either directly cortex, or via In order investigate this hypothesis, field potential signals induced anesthetized rats by electrical stimulation of were recorded simultaneously (anterior part posterior part) (basolateral nucleus cortical nucleus). Single-site paired-pulse was used assess time courses short-term inhibition facilitation each recording site response cortex. Paired-pulse homosynaptic for short interpulse intervals (20-30 ms) all sites, significantly lower degree anterior than other structures. At longer (40-80 ms), observed mainly resulted shortest interval duration (20 basolateral but not nucleus. Double-site then applied determine if can responses stimulation. For heterosynaptic level greater Taken together these data suggest that exerts main inhibitory effect on lesser extent role effects processing information discussed.