Validation and assessment of a blood-donor arm disinfectant containing chlorhexidine and alcohol.

作者: P.-Y. Wong , V.L. Colville , V. White , H.M. Walker , R.A. Morris

DOI: 10.1111/J.1537-2995.2004.03362.X

关键词:

摘要: BACKGROUND:  To minimize the bacterial contamination rate in blood collected from donors, a study was designed to evaluate suitability of single-use chlorhexidine-alcohol antiseptic for donor arm preparation at all collection venues Australia. STUDY DESIGN AND METHODS:  A prospective load on skin performed 616 donors’ arms before and after disinfection using direct swabbing plating technique. Disinfection achieved with swab containing 1 percent chlorhexidine gluconate 75 alcohol, which applied prescribed method. Feedback donors staff obtained questionnaires. RESULTS:  After disinfection, 99 had counts 5 cfu per plate or less, 99.5 10 cfu respectively. The mean colony count 0.39, percentage reduction compared predisinfection. Sixteen (3%) noted transient irritation. majority (64%) preferred not use new disinfectant due difficulty opening packaging an excessive amount solution pack. CONCLUSION:  bacteriologic showed that satisfied requirements Australian Red Cross Blood Service prepare blood-donor venesection. An improvement required it could be acceptable staff.

参考文章(16)
Matthew J. Kuehnert, Virginia R. Roth, N. Rebecca Haley, Kay R. Gregory, Kathy V. Elder, George B. Schreiber, Matthew J. Arduino, Stacey C. Holt, Loretta A. Carson, Shailen N. Banerjee, William R. Jarvis, Transfusion-transmitted bacterial infection in the United States, 1998 through 2000. Transfusion. ,vol. 41, pp. 1493- 1499 ,(2001) , 10.1046/J.1537-2995.2001.41121493.X
Clive R. Seed, Anthea Cheng, Susan L. Ismay, Wayne V. Bolton, Philip Kiely, Trevor J. Cobain, Anthony J. Keller, , Assessing the accuracy of three viral risk models in predicting the outcome of implementing HIV and HCV NAT donor screening in Australia and the implications for future HBV NAT. Transfusion. ,vol. 42, pp. 1365- 1372 ,(2002) , 10.1046/J.1537-2995.2002.00204.X
M. Goldman, G. Roy, N. Fréchette, F. Décary, L. Massicotte, G. Delage, Evaluation of donor skin disinfection methods Transfusion. ,vol. 37, pp. 309- 312 ,(1997) , 10.1046/J.1537-2995.1997.37397240214.X
CK Lee, PL Ho, NK Chan, A Mak, J Hong, CK Lin, None, Impact of donor arm skin disinfection on the bacterial contamination rate of platelet concentrates Vox Sanguinis. ,vol. 83, pp. 204- 208 ,(2002) , 10.1046/J.1423-0410.2002.00219.X
C. P. McDonald, P. Lowe, A. Roy, S. Robbins, S. Hartley, J. F. Harrison, A. Slopecki, N. Verlander, J. A. J. Barbara, Evaluation of donor arm disinfection techniques Vox Sanguinis. ,vol. 80, pp. 135- 141 ,(2001) , 10.1046/J.1423-0410.2001.00029.X
Nathorn Chaiyakunapruk, David L. Veenstra, Benjamin A. Lipsky, Sanjay Saint, Chlorhexidine Compared with Povidone-Iodine Solution for Vascular Catheter–Site Care Annals of Internal Medicine. ,vol. 136, pp. 792- 801 ,(2002) , 10.7326/0003-4819-136-11-200206040-00007
Barbara W. Trautner, Jill E. Clarridge, Rabih O. Darouiche, Skin antisepsis kits containing alcohol and chlorhexidine gluconate or tincture of iodine are associated with low rates of blood culture contamination. Infection Control and Hospital Epidemiology. ,vol. 23, pp. 397- 401 ,(2002) , 10.1086/502073
Michael R. Jacobs, Elizabeth Palavecino, Roslyn Yomtovian, Don't bug me: the problem of bacterial contamination of blood components--challenges and solutions. Transfusion. ,vol. 41, pp. 1331- 1334 ,(2001) , 10.1046/J.1537-2995.2001.41111331.X