Internalization of Exosomes through Receptor-Mediated Endocytosis
作者： Amber Gonda , Janviere Kabagwira , Girish N. Senthil , Nathan R. Wall
DOI: 10.1158/1541-7786.MCR-18-0891
关键词:
摘要: The tumor microenvironment is replete with factors secreted and internalized by surrounding cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that released in greater quantities from cancer than normal cells taken up a variety of cell types. These contain proteins genetic material the origin case tumor-derived exosomes, oncoproteins oncogenes. With increasing understanding role exosomes play basic biology, more clear view potential seen to have therapeutics emerges. However, certain essential aspects exosome function, such as uptake mechanisms, still unknown. Various methods cell-exosome interaction been proposed, but this review focuses on protein-protein interactions facilitate receptor-mediated endocytosis, broadly used mechanism
aacrjournals.org
sci-hub.se 参考文章(149)
Valentina Murdica, Elisa Giacomini, Sofia Makieva, Natasa Zarovni, Massimo Candiani, Andrea Salonia, Riccardo Vago, Paola Viganò, None, In vitro cultured human endometrial cells release extracellular vesicles that can be uptaken by spermatozoa. Scientific Reports. ,vol. 10, pp. 8856- 8856 ,(2020) , 10.1038/S41598-020-65517-9
Jameel M. Inal, Decoy ACE2-expressing extracellular vesicles that competitively bind SARS-CoV-2 as a possible COVID-19 therapy. Clinical Science. ,vol. 134, pp. 1301- 1304 ,(2020) , 10.1042/CS20200623
Pedram Kharaziha, Dimitris Chioureas, Dorothea Rutishauser, George Baltatzis, Lena Lennartsson, Pedro Fonseca, Alireza Azimi, Kjell Hultenby, Roman Zubarev, Anders Ullén, Jeffrey Yachnin, Sten Nilsson, Theocharis Panaretakis, Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Oncotarget. ,vol. 6, pp. 21740- 21754 ,(2015) , 10.18632/ONCOTARGET.3226
Ayuko Hoshino, Bruno Costa-Silva, Tang-Long Shen, Goncalo Rodrigues, Ayako Hashimoto, Milica Tesic Mark, Henrik Molina, Shinji Kohsaka, Angela Di Giannatale, Sophia Ceder, Swarnima Singh, Caitlin Williams, Nadine Soplop, Kunihiro Uryu, Lindsay Pharmer, Tari King, Linda Bojmar, Alexander E. Davies, Yonathan Ararso, Tuo Zhang, Haiying Zhang, Jonathan Hernandez, Joshua M. Weiss, Vanessa D. Dumont-Cole, Kimberly Kramer, Leonard H. Wexler, Aru Narendran, Gary K. Schwartz, John H. Healey, Per Sandstrom, Knut Jørgen Labori, Elin H. Kure, Paul M. Grandgenett, Michael A. Hollingsworth, Maria de Sousa, Sukhwinder Kaur, Maneesh Jain, Kavita Mallya, Surinder K. Batra, William R. Jarnagin, Mary S. Brady, Oystein Fodstad, Volkmar Muller, Klaus Pantel, Andy J. Minn, Mina J. Bissell, Benjamin A. Garcia, Yibin Kang, Vinagolu K. Rajasekhar, Cyrus M. Ghajar, Irina Matei, Hector Peinado, Jacqueline Bromberg, David Lyden, Tumour exosome integrins determine organotropic metastasis Nature. ,vol. 527, pp. 329- 335 ,(2015) , 10.1038/NATURE15756
Bing Liang, Peng Peng, She Chen, Lin Li, Meijun Zhang, Dongyan Cao, Jiaxin Yang, Haixia Li, Ting Gui, Xialu Li, Keng Shen, Characterization and proteomic analysis of ovarian cancer-derived exosomes Journal of Proteomics. ,vol. 80, pp. 171- 182 ,(2013) , 10.1016/J.JPROT.2012.12.029
Mathilde Chivet, Charlotte Javalet, Karine Laulagnier, Béatrice Blot, Fiona J. Hemming, Rémy Sadoul, Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons Journal of extracellular vesicles. ,vol. 3, pp. 24722- 24722 ,(2014) , 10.3402/JEV.V3.24722
Inbal Hazan-Halevy, Daniel Rosenblum, Shiri Weinstein, Osnat Bairey, Pia Raanani, Dan Peer, Cell-specific uptake of mantle cell lymphoma-derived exosomes by malignant and non-malignant B-lymphocytes Cancer Letters. ,vol. 364, pp. 59- 69 ,(2015) , 10.1016/J.CANLET.2015.04.026
Michael Miksa, Rongqian Wu, Weifeng Dong, Padmalaya Das, Derek Yang, Ping Wang, Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis. Shock. ,vol. 25, pp. 586- 593 ,(2006) , 10.1097/01.SHK.0000209533.22941.D0
Salma Khan, Heather Ferguson Bennit, David Turay, Mia Perez, Saied Mirshahidi, Yuan Yuan, Nathan R Wall, Early diagnostic value of survivin and its alternative splice variants in breast cancer BMC Cancer. ,vol. 14, pp. 176- 176 ,(2014) , 10.1186/1471-2407-14-176
V. Muralidharan-Chari, J. W. Clancy, A. Sedgwick, C. D'Souza-Schorey, Microvesicles: mediators of extracellular communication during cancer progression Journal of Cell Science. ,vol. 123, pp. 1603- 1611 ,(2010) , 10.1242/JCS.064386