Inflammation as "common soil" of the multifactorial diseases.
作者： Rossana Scrivo , Massimiliano Vasile , Izabella Bartosiewicz , Guido Valesini
DOI: 10.1016/J.AUTREV.2010.12.006
关键词:
摘要: Inflammation is classically recognized as an essential step for the control of microbial invasion or tissue injury well maintenance homeostasis under a variety noxious conditions. One most intriguing aspect studying inflammation plurality inflammatory mediators that are continuously discovered (microRNAs, adipokines, inflammasomes and danger signals, etc.) their effects on target tissues. Several studies have demonstrated response represents "common soil" multifactorial diseases, encompassing both chronic rheumatic disorders wide conditions including type 2 diabetes, cardiovascular neurodegenerative obesity, cancer, asthma, ageing. While observed in seems to be triggered by infection injury, i.e. main inducers inflammation, other mentioned it appears supported malfunction homeostatic imbalance. In present review, we discuss data emerged from research sustaining diseases.
core.ac.uk
elsevier.com
sci-hub.se 参考文章(40)
Fabio Martinon, Kimberly Burns, Jürg Tschopp, The Inflammasome Molecular Cell. ,vol. 10, pp. 417- 426 ,(2002) , 10.1016/S1097-2765(02)00599-3
P S Whitton, Inflammation as a causative factor in the aetiology of Parkinson's disease. British Journal of Pharmacology. ,vol. 150, pp. 963- 976 ,(2007) , 10.1038/SJ.BJP.0707167
Peter Duewell, Hajime Kono, Katey J. Rayner, Cherilyn M. Sirois, Gregory Vladimer, Franz G. Bauernfeind, George S. Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr, Terje Espevik, Egil Lien, Katherine A. Fitzgerald, Kenneth L. Rock, Kathryn J. Moore, Samuel D. Wright, Veit Hornung, Eicke Latz, NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals Nature. ,vol. 464, pp. 1357- 1361 ,(2010) , 10.1038/NATURE08938
Münevver Serdaroğlu, Haşim Çakırbay, Orhan Değer, Sevil Cengiz, Sibel Kul, The association of anti-CCP antibodies with disease activity in rheumatoid arthritis Rheumatology International. ,vol. 28, pp. 965- 970 ,(2008) , 10.1007/S00296-008-0570-3
Dominique Baeten, Pieter Demetter, Claude A. Cuvelier, Elli Kruithof, Nancy Van Damme, Martine De Vos, Eric M. Veys, Filip De Keyser, Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy. The Journal of Pathology. ,vol. 196, pp. 343- 350 ,(2002) , 10.1002/PATH.1044
Dennis McGonagle, Rik J. U. Lories, Ai Lyn Tan, Michael Benjamin, The concept of a “synovio-entheseal complex” and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond Arthritis & Rheumatism. ,vol. 56, pp. 2482- 2491 ,(2007) , 10.1002/ART.22758
Klaus W. Frommer, Birgit Zimmermann, Florian M. P. Meier, Dirk Schröder, Matthias Heil, Andreas Schäffler, Christa Büchler, Jürgen Steinmeyer, Fabia Brentano, Steffen Gay, Ulf Müller-Ladner, Elena Neumann, Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis. Arthritis & Rheumatism. ,vol. 62, pp. 2886- 2899 ,(2010) , 10.1002/ART.27616
Cornelia M. Weyand, Jörg J. Goronzy, PATHOGENESIS OF RHEUMATOID ARTHRITIS Medical Clinics of North America. ,vol. 81, pp. 29- 55 ,(1997) , 10.1016/S0025-7125(05)70504-6
Andreina Bruno, Elisabetta Pace, Pascal Chanez, Delphine Gras, Isabelle Vachier, Giuseppina Chiappara, Maurizio La Guardia, Stefania Gerbino, Mirella Profita, Mark Gjomarkaj, Leptin and leptin receptor expression in asthma Journal of Allergy and Clinical Immunology. ,vol. 124, pp. 230- 237.e4 ,(2009) , 10.1016/J.JACI.2009.04.032
C. Dostert, V. Petrilli, R. Van Bruggen, C. Steele, B. T. Mossman, J. Tschopp, Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. ,vol. 320, pp. 674- 677 ,(2008) , 10.1126/SCIENCE.1156995