Prevalence of multiresistant Gram‐negative organisms in a surgical hospital in Ho Chi Minh Cit, Vietnam

摘要: Summary Objective  To determine resistance patterns of multiresistant Gram-negative organisms at a surgical hospital in Ho Chi Minh City, Vietnam, order to guide appropriate antibiotic prescribing and improve infection control procedures. Method  All samples sent for microbiological analysis over 3-month period were included. A resource neutral double disc-diffusion test was introduced detect the presence extended-spectrum β-lactamase (ESBL) production. Results  We obtained 350 bacterial isolates from clinical specimens; 87.4% bacteria (GNB). Of these, 88.9% Enterobacteriaceae, which 14.7% produced ESBL. Fifteen (37.5%) these isolated within 48 h admission. Resistance gentamicin ciprofloxacin occurred 70.0% 72.5% those that ESBL 39.5% 38.7% did not. third-generation cephalosporins common: 36.7% all GNB resistant ceftriaxone, 34.0% cefotaxime, 19.6% ceftazidime cefoperazone. Conclusion  Multiresistant are common pose challenge therapy. Successful implementation simple production allowed reporting organisms, interventions. Development antibiotic-prescribing guidelines must take into account patterns. Objectif  Determiner les profils de d'organismes Gram-negatifs dans un hopital chirurgical City au Vietnam afin guider vers une prescription appropriee d'antibiotiques et d'ameliorer procedures controle des infections. Methodes  Tous echantillons soumis l'analyse microbiologique sur periode 3 mois ont ete inclus l’etude. Un sous forme disque diffusion utilise pour mesurer l’etendue du spectre β-lactamases. Resultats  souches bacteriennes isolees d’echantillons cliniques dont 87,4%etaient bacteries Gram-negatives. 88,9% celles-ci etaient Enterobacteriaceae 14,7% produisant β-lactamases large spectre. Quinze (37,5%) d'entre endeans 48 heures d'admission. Les resistances la gentamicine ciprofloxacine observees respectivement chez 70,0% 72,5% organismes 39,5% 38,7% celles qui n'en produisaient pas. La aux cephalosporines 3e generation etait courante: 36,7% toutes gram-negatives resistantes 34%a cefotaxine, 19,6%a ceftazidine 36,7%a gram-negatifs multiresistants sont courants constituent defi l'antibio therapie. L'implementation efficace d'un detection permi decrire: ces organismes, interventions infections. Le developpement directives devrait tenir compte resistance. Objetivo  Determinar los patrones resistencia microorganismos Gram-negativos multiresistentes en quirurgico Ciudad Minh, con el fin orientar prescripcion adecuada antibioticos y mejorar procedimientos para infecciones. Metodos  Se incluyeron todas aquellas muestras recibidas analisis microbiologico dentro periodo meses. realizo una prueba difusion disco doble detectar presencia produccion β-lactamasas espectro ampliado. Resultados  obtuvieron aislados bacterianos partir especimenes clinicos; eran bacterias gram-negativas. De estas, las cuales producian ampliado. Quince ellas fueron aisladas horas despues del ingreso. gentamicina al ciprofloxacino ocurrio productores ampliado aquellos que no lo eran. cefalosporinas tercera generacion era comun: gram-negativas resistentes ceftriaxona, cefotaxima, ceftazidima cefoperazona. Conclusion  Las son comunes plantean reto terapia antibiotica. implementacion exitosa permitio reportar estos microorganismos, realizar correcta e intervenciones infeccion. El desarrollo guias clinicas debe tener cuenta resistencia.