Need for improved antimicrobial and infection control stewardship in Vietnamese intensive care units

作者: M. Johansson , D. M. Phuong , S. M. Walther , H. Hanberger

DOI: 10.1111/J.1365-3156.2011.02753.X

关键词: AcinetobacterCiprofloxacinCeftazidimeMicrobiologyIntensive careAntibiotic resistanceCefotaximeVeterinary medicineImipenemMedicineAmpicillin

摘要: Summary objective Survey of antibiotic consumption, microbial resistance and hygiene precautions in the intensive care units three hospitals northern Vietnam. methods Observational study. Data were collected from microbiological laboratories. Antibiotic consumption was determined based on quantities drugs delivered pharmacy. A protocol to observe application developed used. Bacteria typed tested for drug susceptibility using disc-diffusion method. results The mean 811 defined daily doses per 1000 occupied bed days. most commonly used antibiotics third-generation cephalosporins, followed by carbapenems, amoxicillin ampicillin. Eighty cent bacterial isolates Gram-negative. common pathogens found blood cultures Escherichia coli Klebsiella spp., Pseudomonas Acinetobacter Staphylococcus aureus Enterococcus faecalis. spp. two frequently isolated bacteria respiratory tract all other sources together. Seventy species showed reduced imipenem, 80% ciprofloxacin 89% ceftazidime. Forty-four 49% fully susceptible but 57% samples resistant both cefotaxime. Hygiene poor, fewer than 50% patient contacts incorporated appropriate hand hygiene. conclusion Low poor high level indicate that there is room improvement regarding use infection control.

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