Proposed criteria for mixed-dust pneumoconiosis: definition, descriptions, and guidelines for pathologic diagnosis and clinical correlation.

摘要: We defined mixed-dust pneumoconiosis (MDP) pathologically as a showing dust macules or fibrotic nodules (MDF), with without silicotic (SN), in an individual history of exposure to mixed dust. the latter arbitrarily mixture crystalline silica and nonfibrous silicates. According our definition MDP, therefore, MDF should outnumber SN lung make pathologic diagnosis MDP. In absence confirmation exposure, mineralogic analyses can be used support diagnosis. The clinical MDP requires exclusion other well-defined pneumoconioses, including asbestosis, coal workers' pneumoconiosis, silicosis, hematite miners' welders' berylliosis, hard metal disease, silicate diatomaceous earth carborundum corundum pneumoconiosis. Typical occupations associated include miners, quarry workers, foundry pottery ceramics stonemasons. Irregular opacities are major radiographic findings (ILO 1980), contrast which small rounded predominate. Clinical symptoms nonspecific. must distinguished from variety nonoccupational interstitial pulmonary disorders.