Risk factors and mortality among newborns with persistent pulmonary hypertension.

摘要: OBJECTIVE: To determine the risk factors for persistent pulmonary hypertension of newborns (PPHN) and their influence on mortality. METHODS: This was an observational study conducted at The Children's Hospital & Institute Child Health, Multan, Pakistan, from July 2011 to June 2012.All admitted babies who had respiratory distress, cyanosis evidence hypoxia ABG,s were diagnosed provided that they having right- to- left or bidirectional hemodynamic shunting ductus arteriosus patent foramen ovale along with Tricuspid regurgitation (TR) jet >40 mm Hg echocardiography. All demographic, maternal, antenatal, natal postnatal data recorded a predesigned Performa. RESULTS: There 79 patients, including 61 males 18 females. most common observed in our male sex (72.1%), cesarean section mode delivery (54.2%), positive pressure ventilation while resuscitation (44.2%) birth asphyxia (40.4%) meconium aspiration syndrome (MAS)35.4%. It found (88.8%), cesarean-section (77.7%), distress (RDS) 44.8% sepsis (44.4%) more associated PPHN premature infants than term post infants. Out total death occurred among 7 preterm 14 terms As whole, (71.4%), (57.1%) female (52.4%) major However, (Relative Risk RR=5), (RR=2.5) (RR=2)were be increased mortality CONCLUSION: Male gender, delivery, MAS RDS are any age group. RDS, Birth pre