RAS Proteins and Their Regulators in Human Disease.

作者: Dhirendra K. Simanshu , Dwight V. Nissley , Frank McCormick

DOI: 10.1016/J.CELL.2017.06.009

关键词:

摘要: … of phenotypes now known to be caused by mutations in … deep pocket to which small molecules could bind with high affinity. … -based docking make RAS seem like a more tractable target. …

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