作者: Tamara A. Martino , Peter Liu , Martin Petric , Michael J. Sole
DOI: 10.1128/9781555818326.CH14
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摘要: This chapter presents epidemiologic data on the incidence of myocarditis and dilated cardiomyopathy (DCM) their associations with enteroviruses. The pathogenesis enterovirus-induced heart disease is comprehensively reviewed, particular attention given to experimental studies elucidating viral immunologic mechanisms process. gives an overview pathology, talks about replication in heart, host defense mechanisms, cell-mediated destruction myofibers, virus participation chronic disease, autoimmunity, infection cardiac dysfunction, factors affecting severity. Next, it reviews detection enteroviral patients DCM. It also describes clinical features DCM, discusses evidence that these diseases are two ends same spectrum. Finally, conventional treatments for In addition, role immunosuppression future avenues therapy examined.