Graves' ophthalmopathy in relation to cigarette smoking and ethnic origin.

摘要: OBJECTIVE We aimed to study the effect of cigarette smoking on prevalence and severity Graves' ophthalmopathy (GO). PATIENTS One hundred fifty-five newly diagnosed patients with disease (GD) were clinically by routine biochemical methods. Twenty-five per cent (39) Asian origin. METHODS Eye signs classified according American Thyroid Association Classification. A detailed questionnaire data from hospital notes used calculate an index consumption. RESULTS Thirty-four all had ophthalmopathy, in males (26%) females (36%) did not differ significantly. There was a 42% among Europeans compared 7.7% Asians (P = 0.0002). The overall risk for developing 6.4 (1.78-22.7 confidence interval) times higher than Asians. Corrected ethnic factor increased 2.4 (1.12-5.18, 95% higher. significant dose 0.008). CONCLUSIONS present findings confirm addition show that have substantially greater