Differential regulation of osteogenic differentiation of stem cells on surface roughness gradients.
作者： Ana B Faia Torres , Stefanie Guimond Lischer , Markus Rottmar , Mirren Charnley , T Goren
DOI: 10.1016/J.BIOMATERIALS.2014.07.015
关键词:
摘要: Tissue engineering using scaffold-cell constructs holds the potential to develop functional strategies to regenerate bone. The interface of orthopedic implants with the host tissues is of great importance for its later performance. Thus, the optimization of the implant surface in a way that could stimulate osteogenic differentiation of mesenchymal stem cells (MSCs) is of significant therapeutic interest. The effect of surface roughness of polycaprolactone (PCL) on the osteogenic differentiation of human bone-marrow MSCs was investigated. We prepared …
core.ac.uk
sci-hub.se 参考文章(34)
K Anselme, A Ponche, M Bigerelle, Relative influence of surface topography and surface chemistry on cell response to bone implant materials. Part 2: Biological aspects Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. ,vol. 224, pp. 1487- 1507 ,(2010) , 10.1243/09544119JEIM901
Rahul Singhvi, Gregory Stephanopoulos, Daniel I. C. Wang, Effects of substratum morphology on cell physiology. Biotechnology and Bioengineering. ,vol. 43, pp. 764- 771 ,(1994) , 10.1002/BIT.260430811
Marco Wieland, Babak Chehroudi, Marcus Textor, Donald M. Brunette, Use of Ti-coated replicas to investigate the effects on fibroblast shape of surfaces with varying roughness and constant chemical composition Journal of Biomedical Materials Research. ,vol. 60, pp. 434- 444 ,(2002) , 10.1002/JBM.10059
Albino Martins, Elisabete D. Pinho, Susana Faria, Iva Pashkuleva, Alexandra P. Marques, Rui L. Reis, Nuno M. Neves, Surface Modification of Electrospun Polycaprolactone Nanofiber Meshes by Plasma Treatment to Enhance Biological Performance Small. ,vol. 5, pp. 1195- 1206 ,(2009) , 10.1002/SMLL.200801648
Arnold I. Caplan, Mesenchymal stem cells Journal of Orthopaedic Research. ,vol. 9, pp. 641- 650 ,(1991) , 10.1002/JOR.1100090504
A. Yeo, W. J. Wong, H. H. Khoo, S. H. Teoh, Surface modification of PCL-TCP scaffolds improve interfacial mechanical interlock and enhance early bone formation: An in vitro and in vivo characterization Journal of Biomedical Materials Research Part A. ,vol. 92, pp. 311- 321 ,(2010) , 10.1002/JBM.A.32366
Caroline Seebach, Judith Schultheiss, Kerstin Wilhelm, Johannes Frank, Dirk Henrich, Comparison of six bone-graft substitutes regarding to cell seeding efficiency, metabolism and growth behaviour of human mesenchymal stem cells (MSC) in vitro. Injury-international Journal of The Care of The Injured. ,vol. 41, pp. 731- 738 ,(2010) , 10.1016/J.INJURY.2010.02.017
Albino Martins, Marta L. Alves da Silva, Susana Faria, Alexandra P. Marques, Rui L. Reis, Nuno M. Neves, The influence of patterned nanofiber meshes on human mesenchymal stem cell osteogenesis. Macromolecular Bioscience. ,vol. 11, pp. 978- 987 ,(2011) , 10.1002/MABI.201100012
Mark F Pittenger, Alastair M Mackay, Stephen C Beck, Rama K Jaiswal, Robin Douglas, Joseph D Mosca, Mark A Moorman, Donald W Simonetti, Stewart Craig, Daniel R Marshak, Multilineage Potential of Adult Human Mesenchymal Stem Cells Science. ,vol. 284, pp. 143- 147 ,(1999) , 10.1126/SCIENCE.284.5411.143
J. P. Vacanti, R. Langer, Tissue engineering : Frontiers in biotechnology Science. ,vol. 260, pp. 920- 926 ,(1993)