Streptomyces coelicolor : a Mycelial, Spore-Bearing Prokaryote

摘要: Many bacteria grow rapidly by binary fission, with cell populations that are usually presumed to be virtually identical each other except in cyclerelated processes or very rare events such as transposition DNA rearrangements. Generally, they do not have intracellular compartments. These qualities, along their simple nutrition and exceptional amenability a wide range of types genetic analysis, make them wonderful objects for the investigation many basic biological questions, which may act models higher organisms. On hand, important aspects organisms consequence multicellularity structural complexity. Some indeed also show cellular differentiation, formation endospores Bacillus subtilis discussed chapter Errington being best-known example; few truly multicellular — perhaps most notably Gramnegative myxobacteria, unicellular motile cells cooperate produce sporulating fruiting bodies, Gram-positive actinomycetes, form mycelial colonies on specialized spore-bearing organs develop. How is organisation controlled coordinated? great changes needed account evolution differentiation? Can students eukaryotic developmental biology learn anything from prokaryotic systems vice versa? This discusses current knowledge intensively studied members genus Streptomyces. Much this work has focused S. coelicolor A3 (2), genetically species, though some discoveries been made especially griseus antibioticus, sporulate particularly abundantly.