Neuroimaging Human Drug Addiction

摘要: Drug addiction is a chronic central nervous system disease marked by compulsive drug use despite negative life consequences. Neuroimaging technology has significantly impacted research revealing the complex neural circuits underlying behaviors and symptoms associated with disease. In this chapter, we explore syndrome examining its emotional cognitive behavioral components particular focus on reward valuation inhibitory control brain regions that subserve them. An overview of neurobiological theories provided an attempt made to weave them into unified brain-behavior theoretical model. This model expands traditional concepts emphasize limbic-regulated responses involvement frontal cortex throughout cycle. These recent neurobehavioral advances can help guide development treatment for dependence offer insight neurobiology broader human phenomenology encompasses motivation free will.