Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
作者： Marco Sandri , Claudia Sandri , Alex Gilbert , Carsten Skurk , Elisa Calabria
DOI: 10.1016/S0092-8674(04)00400-3
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摘要: … of Foxo transcription factors and atrogin-1 induction. IGF-1 treatment or AKT overexpression inhibits Foxo … When Foxo activation is blocked by a dominant-negative construct in myotubes …
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