Synthesis, structural and electrochemical characterization of novel 1,3-ketoureas bearing a ferrocenyl group

摘要: Abstract Twenty-two novel 1,3-ketourea derivatives bearing ferrocene moiety were synthesized in good-to-excellent yields (up to 99%) via simple and efficient protocol. This solvent- catalyst-free synthesis was achieved by additions of different ferrocene-containing Mannich bases – 3-(arylamino)-1-ferrocenylpropan-1-ones phenyl isocyanate promoted only ultrasound irradiations at ambient temperature. All 1-aryl-3-phenyl-1-(3-ferrocenyl-3-oxopropyl)ureas characterized standard spectral data (1H NMR, 13C NMR IR), their electrochemical behavior investigated cyclic voltammetry. Detailed single-crystal X-ray diffraction analysis three representative 1,3-ketoureas, among which one crystallized with two independent molecules an asymmetric unit, done.