The ontogeny of substance P- and serotonin-like immunoreactivities in the sexually dimorphic cremaster nucleus of the rat spinal cord.
作者： Bruce W. Newton , MaryAnn A. Romagnano , Robert W. Hamill
DOI: 10.1016/0165-3806(89)90178-8
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摘要: Abstract This study investigates the ontogeny of two transmitter systems which innervate sexually dimorphic cremaster nucleus (CN). Since these arise from separate extra- and intraspinal sources, their ontological sequences differ. In males, substance P (SP) innervates CN motoneurons on postnatal day (P) 0, while serotonin (5-HT) is first observed P2. SP reaches a mature innervation pattern P20, 5-HT maturation prolonged to P40–60. It suggested that part reason for differing rates development within due source innervating fibers; descends brainstem origin. On P6, dorsal processes male so advanced spinal cord may be ‘sexed’ according presence, or female ‘absence’, this pattern. developing adult females, greater than innervation. addition, surrounding motor columns. Compared ventral gray horn nuclei, receives slightly delayed reflection formation muscle.
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