Analysis of the microRNA transcriptome of Daphnia pulex during aging.

作者: Jiabao Hu , Chongyuan Lin , Mengdi Liu , Qiaoqiong Tong , Shanliang Xu

DOI: 10.1016/J.GENE.2018.04.034

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摘要: Abstract Daphnia pulex is an important food organism that exhibits a particular mode of reproduction known as cyclical parthenogenesis (asexual) and sexual reproduction. Regulation the aging process by microRNAs (miRNAs) research hotspot in miRNA studies. To investigate possible role miRNAs regulating senescence, we used Illumina HiSeq to sequence two libraries from 1-day-old (1d) 25-day-old (25d) D. specimens. In total, obtained 11,218,097 clean reads 28,569 unique 1d specimens 11,819,106 44,709 25d Bioinformatic analyses was identify 1335 differentially expressed miRNAs, including 127 exhibited statistically significant differences (P

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