作者: R Carter W Jones , Tobias Moeller-Bertram , Mark S Wallace
DOI: 10.2217/PMT.11.76
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摘要: SUMMARY The practice of delivering analgesic drugs into the intrathecal space has evolved over past several decades from a ‘last-ditch’ therapy for intractable pain in patients with terminal cancer to more widely applied strategy treating chronic nonmalignant as well. This review discusses available safety and efficacy data drug delivery focus on device- user-related issues.