Fatty acid deficiency profile in children with food allergy managed with elimination diets

作者: Luis Aldámiz-Echevarría , Agurtzane Bilbao , Fernando Andrade , Javier Elorz , José Angel Prieto

DOI: 10.1111/J.1651-2227.2008.00963.X

关键词:

摘要: AIM To evaluate plasma fatty acid (FA) composition of children with food allergy undergoing elimination diets that avoided the offending antigens. METHODS Twenty-five (14 male, 11 female) aged 3.8 +/- 1.6 years (range 2-7 years) affected multiple and managed participated in a cross-sectional study. Results acids were compared data obtained 61 healthy children. RESULTS The patients had significantly lower values for content total polyunsaturated acids, omega3 long-chain (p < 0.001) particularly, eicosapentaenoic (EPA) (20:5omega3) docosahexaenoic (DHA) (22:6omega3) 0.001). Moreover, all established indices (essential [EFA] index ((omega3 +omega6)/(omega7 +omega9)) sufficiency (C22:6omega3/C22:5omega6) 0.001)) confirmed presence EFA deficiency. CONCLUSION Children restricted intake foods such as milk, egg, fish vegetables are at risk developing deficiency particularly which especially necessary adequate growth, neurological development cardiovascular health.

参考文章(28)
Janet A Dunstan, Trevor A Mori, Anne Barden, Lawrence J Beilin, Angie L Taylor, Patrick G Holt, Susan L Prescott, Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: A randomized, controlled trial The Journal of Allergy and Clinical Immunology. ,vol. 112, pp. 1178- 1184 ,(2003) , 10.1016/J.JACI.2003.09.009
Jan L Breslow, n−3 Fatty acids and cardiovascular disease The American Journal of Clinical Nutrition. ,vol. 83, ,(2006) , 10.1093/AJCN/83.6.1477S
David F Horrobin, Essential fatty acid metabolism and its modification in atopic eczema The American Journal of Clinical Nutrition. ,vol. 71, ,(2000) , 10.1093/AJCN/71.1.367S
Petra LL Goyens, Mary E Spilker, Peter L Zock, Martijn B Katan, Ronald P Mensink, Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. The American Journal of Clinical Nutrition. ,vol. 84, pp. 44- 53 ,(2006) , 10.1093/AJCN/84.1.44
Susan L Prescott, Philip C Calder, N-3 polyunsaturated fatty acids and allergic disease. Current Opinion in Clinical Nutrition and Metabolic Care. ,vol. 7, pp. 123- 129 ,(2004) , 10.1097/00075197-200403000-00004
Scarlett Salman, Lynn Christie, Wesley Burks, Beverly Mccabe-Sellers, Dietary intakes of children with food allergies: Comparison of the food guide pyramid and the recommended dietary allowances 10th ed The Journal of Allergy and Clinical Immunology. ,vol. 109, ,(2002) , 10.1016/S0091-6749(02)81780-8
Tamás Decsi, Günther Boehm, H. M. Ria Tjoonk, Szilárd Molnár, D. A. Janneke Dijck-Brouwer, Mijna Hadders-Algra, Ingrid A. Martini, Frits A. J. Muskiet, E. Rudy Boersma, Trans isomeric octadecenoic acids are related inversely to arachidonic acid and DHA and positively related to mead acid in umbilical vessel wall lipids Lipids. ,vol. 37, pp. 959- 965 ,(2002) , 10.1007/S11745-006-0987-Y
Undurti N. Das, A defect in the activity of Δ6 and Δ5 desaturases may be a factor in the initiation and progression of atherosclerosis Prostaglandins Leukotrienes and Essential Fatty Acids. ,vol. 76, pp. 251- 268 ,(2007) , 10.1016/J.PLEFA.2007.03.001
A. Fiocchi, G. R. Bouygue, A. Martelli, L. Terracciano, T. Sarratud, Dietary treatment of childhood atopic eczema/dermatitis syndrome (AEDS). Allergy. ,vol. 59, pp. 78- 85 ,(2004) , 10.1111/J.1398-9995.2004.00653.X
Bethany L. Sullivan, Peter G. Williams, Barbara J. Meyer, Biomarker validation of a long-chain omega-3 polyunsaturated fatty acid food frequency questionnaire Lipids. ,vol. 41, pp. 845- 850 ,(2006) , 10.1007/S11745-006-5039-0