Geographic and Individual Correlates of Subclinical Atherosclerosis in an Asymptomatic Rural Appalachian Population

摘要: Abstract Background This study aimed to examine the association between subclinical atherosclerosis (ascertained as coronary artery calcium [CAC]) in asymptomatic individuals Central Appalachian region of United States and individual- geographic-level factors. Materials Methods Data were obtained from participants CAC screening 2012 2016. score was assessed = 0 (no plaque), 1 ≤ 99 (mild 100 399 (moderate plaque) ≥ 400 (severe plaque). Additionally, data on demographics (age, sex race), medical conditions, lifestyle factors family history disease obtained. Further, zip codes place residence for used generate data. Descriptive statistics estimate prevalence CAC, multinomial logistic regression models delineate significant Results Of 1,512 participants, 57.6% had > 0. The mild, moderate severe plaques 31.6%, 16.3% 9.7%, respectively. Demographics (age sex), associated with increased risk atherosclerosis. proportion minority residents significantly plaque (relative ratio 1.06, P 0.04) government assistance decreased mild 0.93, 0.03). Conclusions results imply that a geographic area is relative atherosclerosis, while such risk. However, future or neighborhood-level studies larger sample size are needed further consistency these population.