The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors

作者: CGTP Collaborators SPH Alexander , D Fabbro , E Kelly , N Marrion , JA Peters

DOI: 10.1111/BPH.13353

关键词:

摘要: The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties over 1750 human drug targets with their pharmacology, plus links an open access knowledgebase and ligands (www.guidetopharmacology.org), which more detailed views target ligand properties. full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13353/full. G protein-coupled receptors are one eight major pharmacological into is divided, others being: receptors, ligand-gated ion channels, voltage-gated other nuclear hormone enzymes transporters. These presented nomenclature guidance summary information on best available tools, alongside references suggestions for further reading. published in landscape format order facilitate comparison related targets. It a condensed version material contemporary late 2015, greater detail constantly updated website www.guidetopharmacology.org, superseding data previous Guides Receptors & Channels 2013/14. produced conjunction NC-IUPHAR official IUPHAR classification targets, where appropriate. consolidates previously curated displayed separately IUPHAR-DB GRAC permanent, citable, point-in-time record that will survive database updates.

参考文章(1)
Jefferson W. Tilley, Li Chen, David C. Fry, S. Donald Emerson, Gordon D. Powers, Denise Biondi, Tracey Varnell, Richard Trilles, Robert Guthrie, Francis Mennona, Gerry Kaplan, Ronald A. LeMahieu, Mathew Carson, Ru-Jen Han, C.-M. Liu, Robert Palermo, Grace Ju, Identification of a Small Molecule Inhibitor of the IL-2/IL-2Rα Receptor Interaction Which Binds to IL-2 Journal of the American Chemical Society. ,vol. 119, pp. 7589- 7590 ,(1997) , 10.1021/JA970702X