Pectin-chitosan conjugated nanoliposome as a promising delivery system for neohesperidin: Characterization, release behavior, cellular uptake, and antioxidant property
作者： Mohammad Rezaul Islam Shishir , Naymul Karim , Vemana Gowd , Jiahong Xie , Xiaodong Zheng
DOI: 10.1016/J.FOODHYD.2019.04.059
关键词:
摘要: Neohesperidin (NH) is a flavanone glycoside compound possessing diverse biological activities. However, NH is unstable in physiological condition and poorly soluble in water, and thereby it may show limited bioavailability. The aim of the present study was to facilitate the controlled delivery of NH in simulated gastrointestinal (GI) tract with enhanced cellular uptake using biopolymer conjugation onto nanoliposome (NL). The carrier systems were characterized by dynamic light scattering, HPLC analysis, and Fourier transform infrared …
sci-hub.se 参考文章(62)
Padala Narasimha Murthy, Prasanta Chowdhury, Lilakanta Nath, Suvakanta Dash, Kinetic modeling on drug release from controlled drug delivery systems Acta Poloniae Pharmaceutica. ,vol. 67, pp. 217- 223 ,(2010)
Weilin Liu, Wei Liu, Aiqian Ye, Shengfeng Peng, Fuqiang Wei, Chengmei Liu, Jianzhong Han, Environmental stress stability of microencapsules based on liposomes decorated with chitosan and sodium alginate. Food Chemistry. ,vol. 196, pp. 396- 404 ,(2016) , 10.1016/J.FOODCHEM.2015.09.050
Jin Nam, T. Kyle Vanderlick, Paul A. Beales, Formation and dissolution of phospholipid domains with varying textures in hybrid lipo-polymersomes Soft Matter. ,vol. 8, pp. 7982- 7988 ,(2012) , 10.1039/C2SM25646K
Dalia I. Hamdan, Mona F. Mahmoud, Michael Wink, Assem M. El-Shazly, Effect of hesperidin and neohesperidin from bittersweet orange (Citrus aurantium var. bigaradia) peel on indomethacin-induced peptic ulcers in rats. Environmental Toxicology and Pharmacology. ,vol. 37, pp. 907- 915 ,(2014) , 10.1016/J.ETAP.2014.03.006
Soha Jeon, Cha Young Yoo, Soo Nam Park, Improved stability and skin permeability of sodium hyaluronate-chitosan multilayered liposomes by Layer-by-Layer electrostatic deposition for quercetin delivery Colloids and Surfaces B: Biointerfaces. ,vol. 129, pp. 7- 14 ,(2015) , 10.1016/J.COLSURFB.2015.03.018
Kanokporn Burapapadh, Hirofumi Takeuchi, Pornsak Sriamornsak, Novel pectin-based nanoparticles prepared from nanoemulsion templates for improving in vitro dissolution and in vivo absorption of poorly water-soluble drug. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 82, pp. 250- 261 ,(2012) , 10.1016/J.EJPB.2012.07.010
Ji-Yeon Chun, Mi-Jung Choi, Sang-Gi Min, Jochen Weiss, Formation and stability of multiple-layered liposomes by layer-by-layer electrostatic deposition of biopolymers Food Hydrocolloids. ,vol. 30, pp. 249- 257 ,(2013) , 10.1016/J.FOODHYD.2012.05.024
Xiuling Li, Hongbin Xiao, Xinmiao Liang, Dazhuo Shi, Jiangang Liu, LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii. Journal of Pharmaceutical and Biomedical Analysis. ,vol. 34, pp. 159- 166 ,(2004) , 10.1016/J.JAPNA.2003.08.002
Oleg Lunov, Tatiana Syrovets, Cornelia Loos, Johanna Beil, Michael Delacher, Kyrylo Tron, G. Ulrich Nienhaus, Anna Musyanovych, Volker Mailänder, Katharina Landfester, Thomas Simmet, Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line ACS Nano. ,vol. 5, pp. 1657- 1669 ,(2011) , 10.1021/NN2000756
Kimihisa Itoh, Noriko Hirata, Megumi Masuda, Shunsuke Naruto, Kazuya Murata, Keitaro Wakabayashi, Hideaki Matsuda, Inhibitory effects of Citrus hassaku extract and its flavanone glycosides on melanogenesis. Biological & Pharmaceutical Bulletin. ,vol. 32, pp. 410- 415 ,(2009) , 10.1248/BPB.32.410