Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents

作者: Gregg W. Stone , Jeffrey W. Moses , Stephen G. Ellis , Joachim Schofer , Keith D. Dawkins

DOI: 10.1056/NEJMOA067193

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摘要: A b s t r ac Results The 4-year rates of stent thrombosis were 1.2% in the sirolimus-stent group versus 0.6% bare-metal-stent (P = 0.20) and 1.3% paclitaxel-stent 0.9% 0.30). However, after 1 year, there five episodes patients with sirolimus-eluting stents none bare-metal 0.025) nine paclitaxel-eluting two 0.028). target-lesion revascularization markedly reduced both group, as compared groups. death or myocardial infarction did not differ significantly between groups drug-eluting those stents. Conclusions Stent year was more common than Both associated a marked reduction revascularization. There no significant differences cumulative at 4 years.

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