Mineral phase deposition on pectin microspheres

摘要: Abstract The nucleation of apatite and calcium phosphates onto natural polysaccharides containing carboxyl groups can be obtained by immersion in biomimetic solutions. deposition hydroxyapatite has been recently described also on pectin, pectin–apatite hybrid gels were proposed as scaffolds for bone tissue regeneration. In this work, injectable phosphate/pectin microspheres prepared to promote both the process biomineralization controlled release encapsulated cells, genes, enzymes, proteins or drugs pathological situ. Pectin with different formulations from aqueous solutions using an extrusion system, incubated H2O SBF 14 days. presence excess CaCl2, deriving preparation process, was determinant promoting SBF, whereas no mineral detected pectin extensively purified after preparation. occurred 14 days evaluated through ESEM–EDS analysis FT-IR spectroscopy.