作者: Michael Kriegler , Kirston E. Koths , Carl Perez , Robert F. Halenbeck , David A. Jewell
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摘要: Methods and materials are disclosed for the production of purified, active recombinant human neutrophil protease, PR-3, via activation a pro-form herein referred to as proPR-3. Human PR-3 is useful discovering inhibitors excessive release mature, TNFα. Also methods identification conversion TNFα its mature form.