Growth Hormone (GH) and Cardiovascular System.

摘要: This review describes the positive effects of growth hormone (GH) on cardiovascular system. We analyze why vascular endothelium is a real internal secretion gland, whose inflammation first step for developing atherosclerosis, as well mechanisms by which GH acts vessels improving oxidative stress imbalance and endothelial dysfunction. also report how coronary arterial disease heart failure, peripheral disease, inducing neovascularization process that finally increases flow in ischemic tissues. include some preliminary data from trial or placebo given to elderly people suffering critical limb ischemia, showing benefits plasma markers inflammation, safety administration during short periods time, even diabetic patients. Klotho strongly related GH, inducing, after being released damaged endothelium, pituitary most likely repair injury show can help wound healing increasing blood neurotrophic factors. In summary, we postulate short-term could be useful treat diseases.