Interactions of Ethyl Alcohol and Other Drugs

摘要: Ethyl alcohol is a potent pharmacologic agent with wide variety of biochemical and neurophysiological effects, most marked in the central nervous system but by no means restricted to it. The mechanisms these pharmacological actions are not only poorly understood assumed involve spectrum enzyme effects addition physiochemical on other parameters drug activity such as membrane permeability, electrolyte activities, so on. Consequently, it surprising that ethyl should both affect action drugs be affected them. These interactions run gamut from antagonistic mutual neutralization simple similar actual potentiating where total effect two greater than sum alone. even less well those for individual drugs. purpose chapter review studies dealing empirical data describing behavorial combinations also which may illuminate interactions.