作者: M. Ulfendahl , Eliza Chan , William B. McConnaughey , Scott Prost-Domasky , Elliot L. Elson
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摘要: The function of the hearing organ is based on mechanical processes occurring at cellular level. properties guinea-pig isolated sensory cells were investigated using two different techniques. stiffness outer hair along longitudinal axis was measured by compressing cell body stiffness-calibrated quartz fibres. For with a mean length 69 µm, axial compression 1.1±0.8 mN/m (±SD). There an inverse relation between and length. membrane perpendicular to indenting known force. lateral indentation 3.3±1.5 (±SD) for 64 µm. Longer less stiff than short cells. Modelling as shell bending resistance, finite element calculations demonstrated that correlated well stiffness, simple isotropic model sufficient explain experimental observations despite stress strain states produced results imply may originate from same cytoskeletal structures. It suggested are designed influence sound-induced motion reticular lamina. In such system, changes bodies could actively control efficiency coupling basilar important mechanoelectrical transduction sites surface organ.