Lesions of substantia nigra retard pavlovian somatomotor learning but do not affect autonomic conditioning
作者： Kuen Kao , D.A. Powell
DOI: 10.1016/0304-3940(86)90653-1
关键词:
摘要: New Zealand albino rabbits with bilateral radio frequency lesions of the substantia nigra (SN) were compared sham-operated animals on a pavlovian conditioning task in which eyeblink (EB) and heart rate (HR) responses concomitantly assessed. Lesions SN increased number trials required to reach an EB learning criterion but left HR conditioned response intact. These results together other reports literature suggest that extrapyramidal motor structures are involved mediating somatomotor not autonomic learning.
elsevier.com
sci-hub.se 参考文章(17)
John W. Moore, John E. Desmond, Neil E. Berthier, The Metencephalic Basis of the Conditioned Nictitating Membrane Response Springer, Boston, MA. pp. 459- 482 ,(1982) , 10.1007/978-1-4757-0701-4_33
Philippe Richard, Ivan Urban, A stereotaxic atlas of the New Zealand rabbit's brain ,(1972)
S Zola-Morgan, LR Squire, Preserved learning in monkeys with medial temporal lesions: sparing of motor and cognitive skills. The Journal of Neuroscience. ,vol. 4, pp. 1072- 1085 ,(1984) , 10.1523/JNEUROSCI.04-04-01072.1984
M.E. Rosenfield, J.W. Moore, Red nucleus lesions disrupt the classically conditioned nictitating membrane response in rabbits. Behavioural Brain Research. ,vol. 10, pp. 393- 398 ,(1983) , 10.1016/0166-4328(83)90043-8
D.G. Lavond, J.S. Lincoln, D.A. McCormick, R.F. Thompson, Effect of bilateral lesions of the dentate and interpositus cerebellar nuclei on conditioning of heart-rate and nictitating membrane/eyelid responses in the rabbit. Brain Research. ,vol. 305, pp. 323- 330 ,(1984) , 10.1016/0006-8993(84)90438-4
Herbert Weingartner, Stanley Burns, Rita Diebel, Peter A. LeWitt, Cognitive impairments in Parkinson's disease: Distinguishing between effort-demanding and automatic cognitive processes Psychiatry Research. ,vol. 11, pp. 223- 235 ,(1984) , 10.1016/0165-1781(84)90071-4
L R Squire, The neuropsychology of human memory. Annual Review of Neuroscience. ,vol. 5, pp. 241- 273 ,(1982) , 10.1146/ANNUREV.NE.05.030182.001325
D.A. Powell, Donald Mankowski, Shirley Buchanan, Concomitant heart rate and corneoretinal potential conditioning in the rabbit (Oryctolagus Cuniculus): Effects of caudate lesions Physiology & Behavior. ,vol. 20, pp. 143- 150 ,(1978) , 10.1016/0031-9384(78)90066-5
Jann S. Lincoln, David A. McCormick, Richard F. Thompson, Ipsilateral cerebellar lesions prevent learning of the classically conditioned nictitating membrane/eyelid response Brain Research. ,vol. 242, pp. 190- 193 ,(1982) , 10.1016/0006-8993(82)90510-8
Shirley L. Buchanan, D. A. Powell, Cingulate cortex: its role in Pavlovian conditioning. Journal of Comparative and Physiological Psychology. ,vol. 96, pp. 755- 774 ,(1982) , 10.1037/H0077925