Nutraceuticals in diabetes and metabolic syndrome.

摘要: Metabolic syndrome represents a clustering of risk factors related to an elevated cardiovascular disease and type 2 diabetes. Occurrence both metabolic diabetes their vascular complications share several pathogenetic features including subclinical, low-grade inflammation, altered oxidative/antioxidant status, persistent platelet activation. Despite the availability multiple interventions counteract these changes, appropriate diet, regular exercise, weight control drugs, epidemiological data are witnessing growing trend problem, reflecting multifactorial nature diseases as well scarce compliance patients established strategies. Several nutraceuticals used in clinical practice have been shown target pathogenesis mellitus, favorably modulate number biochemical endpoints. These compounds include antioxidant vitamins, such vitamins C E, flavonoids, vitamin D, conjugated linoleic acid, omega-3 fatty acids, minerals chromium magnesium, alpha-lipoic phytoestrogens, dietary fibers. areas concern exist regarding use supplements this setting, product standardization, definition optimal dosing regimen, potential side effects, drug interactions, need for evidence-based indications.