In vitro susceptibility of some species of yeasts and filamentous fungi to essential oils of Salvia officinalis
作者： Eugénia Pinto , Lígia Ribeiro Salgueiro , Carlos Cavaleiro , Ana Palmeira , Maria José Gonçalves
DOI: 10.1016/J.INDCROP.2007.02.004
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摘要: Abstract Composition and antifungal activity of Salvia officinalis essential oil were studied. Three samples oils obtained by hydrodistillation from aerial parts plants grown in Portugal one commercial sample analysed gas chromatography (GC) chromatography–mass spectrometry (GC–MS). Quantitative differences observed the compositions, particularly amounts cis-thujone (8.8–37.1%) camphor (11.6–23.4%). Antifungal was evaluated minimal inhibitory concentrations (MIC) lethal (MLC) determinations against Candida (four clinical isolates four ATCC type strains), dermatophytes (five strains) other filamentous fungi (Penicillium, Aspergillus, Cladosporium Fusarium). The exhibited a broad spectrum, with higher dermatophyte strains. 10.4% 20.5% most active showed fungicidal activity, MIC MLC values 0.63 μl/ml, Sage products, low content thujones, may be an alternative as agents different areas.
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