作者: Pillai Vijayasingham , Li-Cher Loh , Sree Raman , Tarmizi Thayaparan , Pek-Ngor Teh
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摘要: Perceived breathlessness played an important role in guiding treatment asthma. We developed a simple, user-friendly method of scoring perception dyspnoea (POD) using incentive spirometer, Triflo II (Tyco Healthcare, Mansfield, USA) by means repetitive inspiratory efforts achieved within three minutes 175 normal healthy subjects and 158 asthmatic patients mild (n=26), moderate (n=78) severe (n=54). Severity was stratified according to GINA guideline. The mean POD index subjects, mild, severity were: 6 (4-7) 16 (9-23), 25 (14-37), 57 (14-100) respectively (p<0.001 One-Way ANOVA). Based on 17 20 intraclass correlation coefficients for were high. In 14 randomized receiving nebulised b(2)-agonist or saline crossover, double-blind study, % FEV(1) change correlated with changes [r(s) -0.46, p=0.012]. Finally, when compared 6-minutes walking test (6MWT) open label respiratory 21 [r(s)= 0.58 (0.17 0.81) (p=0.007] 26 [0.50 (0.13 0.75) (p=0.008)]. concluded that this is discriminative between varying from reproducible, responsive bronchodilator effect, comparable 6MWT. Taken together, it has the potential score disability asthma effectively simply.