Hyperphagia, lower body temperature, and reduced running wheel activity precede development of morbid obesity in New Zealand obese mice.
作者： Hella S. Jürgens , Annette Schürmann , Reinhart Kluge , Sylvia Ortmann , Susanne Klaus
DOI: 10.1152/PHYSIOLGENOMICS.00252.2005
关键词:
摘要: Among polygenic mouse models of obesity, the New Zealand obese (NZO) exhibits most severe phenotype, with fat depots exceeding 40% total body weight at age 6 mo. Here we dissect...
sci-hub.se 参考文章(38)
L D Clark, Activity and body-weight relationships in genetically obese animals. Biological Psychiatry. ,vol. 4, pp. 247- ,(1972)
J. B. Young, L. Landsberg, Diminished sympathetic nervous system activity in genetically obese (ob/ob) mouse American Journal of Physiology-endocrinology and Metabolism. ,vol. 245, ,(1983) , 10.1152/AJPENDO.1983.245.2.E148
Patrick K. Gallagher, John P. Sanders, Handbook of thermal analysis and calorimetry Elsevier. ,(1998) , 10.1016/S1573-4374(03)80009-2
K. Subrahmanyam, Metabolism in the New Zealand strain of obese mice Biochemical Journal. ,vol. 76, pp. 548- 556 ,(1960) , 10.1042/BJ0760548
J. A. Levine, Interindividual variation in posture allocation: possible role in human obesity. Science. ,vol. 307, pp. 584- 586 ,(2005) , 10.1126/SCIENCE.1106561
Maria Collin, Marie-Louise Håkansson-Ovesjö, Ilga Misane, Sven Ove Ögren, Björn Meister, Decreased 5-HT transporter mRNA in neurons of the dorsal raphe nucleus and behavioral depression in the obese leptin-deficient ob/ob mouse Molecular Brain Research. ,vol. 81, pp. 51- 61 ,(2000) , 10.1016/S0169-328X(00)00167-4
Harrie F.P. Joosten, Piet H.W. van der Kroon, Growth pattern and behavioral traits associated with the development of the obese-hyperglycemic syndrome in mice () Metabolism. ,vol. 23, pp. 1141- 1147 ,(1974) , 10.1016/0026-0495(74)90030-4
Robert A Koza, Kevin Flurkey, Dawn M Graunke, Christopher Braun, Huei-Ju Pan, Peter C Reifsnyder, Leslie P Kozak, Edward H Leiter, Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity. Metabolism-clinical and Experimental. ,vol. 53, pp. 799- 808 ,(2004) , 10.1016/J.METABOL.2003.12.024
Patrick C. Even, Asghar Mokhtarian, Agnes Pele, Practical aspects of indirect calorimetry in laboratory animals Neuroscience & Biobehavioral Reviews. ,vol. 18, pp. 435- 447 ,(1994) , 10.1016/0149-7634(94)90056-6
K.-H. Rudorff, H. Huchzermeyer, R. Windeck, W. Staib, Über den Einfluß von Insulin auf die Alaningluconeogenese in der isoliert perfundierten Leber von New Zealand Obese Mice FEBS Journal. ,vol. 16, pp. 481- 486 ,(1970) , 10.1111/J.1432-1033.1970.TB01106.X