摘要: RECENT advances in molecular genetics have had a great deal of influence on evolutionary theory, and particular, the neutral mutation-random drift hypothesis evolution1,2 has stimulated much interest. The concept mutant substitution population by random genetic can be extended to include fixation very slightly deleterious mutations which more chance being selected against than for3,4. If this class is important, we predict that evolution rapid small populations or at time speciation5. Here I shall organize observed facts indicate fact important.