Effect of Perioperative Transfusion on Recurrence and Survival after Gastric Cancer Resection: A 7-Institution Analysis of 765 Patients from the US Gastric Cancer Collaborative

摘要: Background The prognostic effect of perioperative blood transfusion on recurrence and survival in patients undergoing resection gastric adenocarcinoma (GAC) remains controversial. Study Design All who underwent for GAC from 2000 to 2012 at the 7 institutions US Gastric Cancer Collaborative were identified. recurrence-free (RFS) overall (OS) context adverse clinicopathologic variables was examined by univariate multivariate regression analyses. Results Of 965 patients, 765 curative intent R0 resection. Median follow-up 44 months; 30-day mortalities excluded. estimated loss (EBL) 200 mL, 168 (22%) received allogeneic transfusions. Transfused less likely receive adjuvant therapy (44% vs 56%; p = 0.01). Transfusion associated with significantly decreased median RFS (13.5 37.2 months, p Conclusions Perioperative is OS after cancer, independent factors. This supports judicious use during cancer.