Antigenic characterization of Tettnang virus: complications caused by passage of the virus in mice from a colony enzootically infected with mouse hepatitis virus.

作者: Abigail L. Smith , Andrew J. Main , Jordi Casals

DOI: 10.4269/AJTMH.1983.32.1172

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摘要: Neutralization assays were undertaken for the purpose of antigenically characterizing three strains Tettnang virus from two geographic regions. The previously reported relationship to mouse hepatitis (MHV) was confirmed. However, precise prototype MHV obscured in our study by finding that isolates had been passaged mice a colony subclinically infected with MHV. An Egyptian strain which not reciprocally related neurotropic JHM Our data stress importance microbiological monitoring apparently healthy laboratory animals used virologic research.

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